Hyaluronidase 1500iu is a highly purified enzyme preparation used in aesthetic medicine to break down hyaluronic acid (HA). It is commonly used by qualified aesthetics practitioners to manage complications from HA dermal fillers, such as vascular occlusion, lump formation, or overcorrection.  Packaged in a convenient 1ml format, Hyaluronidase ensures a quick and controlled way to restore natural aesthetics.

This product is a prescription only medicine.  It is intended only for trained, competent, and appropriately qualified injectors who understand its indications and emergency protocols.

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Benefits

  • Rapid breakdown of HA fillers, supporting emergency management and corrective treatments.

  • Essential agent for vascular occlusion protocols, helping restore blood flow when used within clinical guidelines.

  • Offers precision correction, ideal for dissolving small irregularities or asymmetries.

  • Supports safe and compliant practice, giving practitioners confidence in managing complications.

  • Versatile clinical use, suitable for both elective and emergency filler dissolution (as assessed by the prescriber).

Features

  • Strength: 1500iu Hyaluronidase

  • Form: Lyophilised powder for reconstitution

  • Use: Prescription-only medicine (POM)

  • High enzymatic potency for rapid HA degradation

  • Suitable for emergency and selective dissolving

  • Designed for trained prescribers in aesthetic medicine

Why Choose

Hyaluronidase is a critical safety medication in clinics offering hyaluronic acid filler procedures. Aesthetics practitioners choose 1500iu formulations because they provide:

  • Consistent breakdown performance in urgent corrective cases

  • High purity and reliability

  • Trusted use in medical aesthetics worldwide

  • Essential inclusion in emergency kits for filler-related complications

Whether used for precision refinement or urgent intervention, Hyaluronidase allows practitioners to maintain high standards of patient safety and aesthetic outcomes.

Common Uses

Qualified prescribers may use Hyaluronidase 1500iu for:

  • Managing suspected vascular occlusion following HA filler injection

  • Dissolving overfilled areas

  • Correcting asymmetry or uneven filler placement

  • Treating persistent lumps or nodules

  • Removing migrated filler

  • Corrective work after filler performed elsewhere (“dissolve and refill” protocols)

How It Works

Hyaluronidase is an enzyme that breaks down hyaluronic acid molecules in the dermis or subcutaneous tissue.

1. Hydrolysis of HA Chains

It cleaves the glycosidic bonds within hyaluronic acid, reducing its viscosity and structural integrity.

2. Rapid Dispersion and Absorption

Once the HA is broken down, the body naturally absorbs and clears the remaining fragments.

3. Effective for Filler Reversal

Because most modern dermal fillers are HA-based, Hyaluronidase remains the leading agent for controlled filler dissolution in both emergency and elective correction.

Can it dissolve all dermal fillers?
No. It dissolves hyaluronic acid–based fillers but does not break down non-HA fillers.
Do I need emergency equipment when using it?
Yes. As with any injectable medicine, appropriate emergency drugs, protocols, and training are essential.
How fast does it work?
The effects can begin rapidly once administered, although timing varies by treatment area and clinical scenario.
Can Hyaluronidase be used electively for cosmetic refinement?
Yes—qualified practitioners may use it electively for correcting asymmetry, lumps, or overfilling after clinical assessment.
Is a patch test required?
A patch test may be recommended depending on clinical protocols and individual patient considerations.